M 1 -positive allosteric modulators lacking agonist activity provide the optimal profile for enhanci...
M 1 -positive allosteric modulators lacking agonist activity provide the optimal profile for enhancing cognition
About this item
Full title
M 1 -positive allosteric modulators lacking agonist activity provide the optimal profile for enhancing cognition
Author / Creator
Publisher
England
Journal title
Neuropsychopharmacology (New York, N.Y.), 2018-07, Vol.43 (8), p.1763
Language
English
Formats
Publication information
Publisher
England
Subjects
More information
Scope and Contents
Contents
Highly selective positive allosteric modulators (PAMs) of the M
subtype of muscarinic acetylcholine receptor have emerged as an exciting new approach for improving cognitive function in patients suffering from Alzheimer's disease and schizophrenia. However, excessive activation of M
is known to induce seizure activity and have actions in the...
Alternative Titles
Full title
M 1 -positive allosteric modulators lacking agonist activity provide the optimal profile for enhancing cognition
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmed_primary_29581537
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_29581537
Other Identifiers
E-ISSN
1740-634X
DOI
10.1038/s41386-018-0033-9
