GABA A receptor signalling mechanisms revealed by structural pharmacology
GABA A receptor signalling mechanisms revealed by structural pharmacology
About this item
Full title
GABA A receptor signalling mechanisms revealed by structural pharmacology
Author / Creator
Publisher
England
Journal title
Nature (London), 2019-01, Vol.565 (7740), p.454
Language
English
Formats
Publication information
Publisher
England
Subjects
More information
Scope and Contents
Contents
Type-A γ-aminobutyric (GABA
) receptors are ligand-gated chloride channels with a very rich pharmacology. Some of their modulators, including benzodiazepines and general anaesthetics, are among the most successful drugs in clinical use and are common substances of abuse. Without reliable structural data, the mechanistic basis for the pharmacolog...
Alternative Titles
Full title
GABA A receptor signalling mechanisms revealed by structural pharmacology
Authors, Artists and Contributors
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Record Identifier
TN_cdi_pubmed_primary_30602790
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_30602790
Other Identifiers
E-ISSN
1476-4687
DOI
10.1038/s41586-018-0832-5
