BIN1 recovers tauopathy-induced long-term memory deficits in mice and interacts with Tau through Thr...
BIN1 recovers tauopathy-induced long-term memory deficits in mice and interacts with Tau through Thr 348 phosphorylation
About this item
Full title
Author / Creator
Sartori, Maxime , Mendes, Tiago , Desai, Shruti , Lasorsa, Alessia , Herledan, Adrien , Malmanche, Nicolas , Mäkinen, Petra , Marttinen, Mikael , Malki, Idir , Chapuis, Julien , Flaig, Amandine , Vreulx, Anaïs-Camille , Ciancia, Marion , Amouyel, Philippe , Leroux, Florence , Déprez, Benoit , Cantrelle, François-Xavier , Maréchal, Damien , Pradier, Laurent , Hiltunen, Mikko , Landrieu, Isabelle , Kilinc, Devrim , Herault, Yann , Laporte, Jocelyn and Lambert, Jean-Charles
Publisher
Germany
Journal title
Language
English
Formats
Publication information
Publisher
Germany
More information
Scope and Contents
Contents
The bridging integrator 1 gene (BIN1) is a major genetic risk factor for Alzheimer's disease (AD). In this report, we investigated how BIN1-dependent pathophysiological processes might be associated with Tau. We first generated a cohort of control and transgenic mice either overexpressing human MAPT (TgMAPT) or both human MAPT and BIN1 (TgMAPT;TgBI...
Alternative Titles
Full title
BIN1 recovers tauopathy-induced long-term memory deficits in mice and interacts with Tau through Thr 348 phosphorylation
Authors, Artists and Contributors
Author / Creator
Mendes, Tiago
Desai, Shruti
Lasorsa, Alessia
Herledan, Adrien
Malmanche, Nicolas
Mäkinen, Petra
Marttinen, Mikael
Malki, Idir
Chapuis, Julien
Flaig, Amandine
Vreulx, Anaïs-Camille
Ciancia, Marion
Amouyel, Philippe
Leroux, Florence
Déprez, Benoit
Cantrelle, François-Xavier
Maréchal, Damien
Pradier, Laurent
Hiltunen, Mikko
Landrieu, Isabelle
Kilinc, Devrim
Herault, Yann
Laporte, Jocelyn
Lambert, Jean-Charles
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmed_primary_31065832
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_31065832
Other Identifiers
E-ISSN
1432-0533
DOI
10.1007/s00401-019-02017-9
