Conformational transitions of a neurotensin receptor 1-G i1 complex
Conformational transitions of a neurotensin receptor 1-G i1 complex
About this item
Full title
Conformational transitions of a neurotensin receptor 1-G i1 complex
Author / Creator
Publisher
England
Journal title
Nature (London), 2019-08, Vol.572 (7767), p.80
Language
English
Formats
Publication information
Publisher
England
Subjects
More information
Scope and Contents
Contents
Neurotensin receptor 1 (NTSR1) is a G-protein-coupled receptor (GPCR) that engages multiple subtypes of G protein, and is involved in the regulation of blood pressure, body temperature, weight and the response to pain. Here we present structures of human NTSR1 in complex with the agonist JMV449 and the heterotrimeric G
protein, at a resolution o...
Alternative Titles
Full title
Conformational transitions of a neurotensin receptor 1-G i1 complex
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmed_primary_31243364
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_31243364
Other Identifiers
E-ISSN
1476-4687
DOI
10.1038/s41586-019-1337-6
