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An intrinsic role of IL-33 in T reg cell-mediated tumor immunoevasion

An intrinsic role of IL-33 in T reg cell-mediated tumor immunoevasion

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_31844326

An intrinsic role of IL-33 in T reg cell-mediated tumor immunoevasion

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Publication information

Publisher

United States

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Scope and Contents

Contents

Regulatory T (T
) cells accumulate into tumors, hindering the success of cancer immunotherapy. Yet, therapeutic targeting of T
cells shows limited efficacy or leads to autoimmunity. The molecular mechanisms that guide T
cell stability in tumors remain elusive. In the present study, we identify a cell-intrinsic role of the alarmin interleuk...

Alternative Titles

Full title

An intrinsic role of IL-33 in T reg cell-mediated tumor immunoevasion

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmed_primary_31844326

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_31844326

Other Identifiers

E-ISSN

1529-2916

DOI

10.1038/s41590-019-0555-2

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