Structural plasticity of SARS-CoV-2 3CL M pro active site cavity revealed by room temperature X-ray...
Structural plasticity of SARS-CoV-2 3CL M pro active site cavity revealed by room temperature X-ray crystallography
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England
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English
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England
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The COVID-19 disease caused by the SARS-CoV-2 coronavirus has become a pandemic health crisis. An attractive target for antiviral inhibitors is the main protease 3CL M
due to its essential role in processing the polyproteins translated from viral RNA. Here we report the room temperature X-ray structure of unliganded SARS-CoV-2 3CL M
, reveali...
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Structural plasticity of SARS-CoV-2 3CL M pro active site cavity revealed by room temperature X-ray crystallography
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TN_cdi_pubmed_primary_32581217
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_32581217
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E-ISSN
2041-1723
DOI
10.1038/s41467-020-16954-7