Ha-Ras V12 -Induced Multilayer Cellular Aggregates Is Mediated by Rac1 Activation Rather Than YAP Ac...
Ha-Ras V12 -Induced Multilayer Cellular Aggregates Is Mediated by Rac1 Activation Rather Than YAP Activation
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Author / Creator
Publisher
Switzerland
Journal title
Language
English
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Publication information
Publisher
Switzerland
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Scope and Contents
Contents
We demonstrate that Ha-Ras
overexpression induces the nuclear translocation of Hippo effector Yes-associated protein (YAP) in MDCK cells via the hippo-independent pathway at the confluent stage. Ha-Ras
overexpression leads to the downregulation of Caveolin-1 (Cav1) and the disruption of junction integrity. It has been shown that the disruptio...
Alternative Titles
Full title
Ha-Ras V12 -Induced Multilayer Cellular Aggregates Is Mediated by Rac1 Activation Rather Than YAP Activation
Authors, Artists and Contributors
Author / Creator
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Primary Identifiers
Record Identifier
TN_cdi_pubmed_primary_35625714
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_35625714
Other Identifiers
ISSN
2227-9059
E-ISSN
2227-9059
DOI
10.3390/biomedicines10050977
