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DNA Methyltransferase Inhibitor 5-AZA-DC Regulates TGF β 1-Mediated Alteration of Neuroglial Cell Fu...

DNA Methyltransferase Inhibitor 5-AZA-DC Regulates TGF β 1-Mediated Alteration of Neuroglial Cell Fu...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_36211817

DNA Methyltransferase Inhibitor 5-AZA-DC Regulates TGF β 1-Mediated Alteration of Neuroglial Cell Functions after Oxidative Stress

About this item

Full title

DNA Methyltransferase Inhibitor 5-AZA-DC Regulates TGF β 1-Mediated Alteration of Neuroglial Cell Functions after Oxidative Stress

Publisher

United States

Journal title

Oxidative medicine and cellular longevity, 2022, Vol.2022, p.9259465

Language

English

Formats

Publication information

Publisher

United States

More information

Scope and Contents

Contents

5-AZA-DC is an efficient methylation inhibitor that inhibits methylation of target DNA. In this study, we explored the effects of 5-AZA-DC on the regulation of TGF
1 on target genes in neuroglial cell, as well as neuroglial cell functions under oxidative stress. The oxidative stress was constructed by editing CRISPR/Cas9 for knock out Ang-1 and...

Alternative Titles

Full title

DNA Methyltransferase Inhibitor 5-AZA-DC Regulates TGF β 1-Mediated Alteration of Neuroglial Cell Functions after Oxidative Stress

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmed_primary_36211817

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_36211817

Other Identifiers

E-ISSN

1942-0994

DOI

10.1155/2022/9259465

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