Absolute quantification of single-base m 6 A methylation in the mammalian transcriptome using GLORI
Absolute quantification of single-base m 6 A methylation in the mammalian transcriptome using GLORI
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Author / Creator
Liu, Cong , Sun, Hanxiao , Yi, Yunpeng , Shen, Weiguo , Li, Kai , Xiao, Ye , Li, Fei , Li, Yuchen , Hou, Yongkang , Lu, Bo , Liu, Wenqing , Meng, Haowei , Peng, Jinying , Yi, Chengqi and Wang, Jing
Publisher
United States
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Language
English
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Publisher
United States
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Contents
N
-methyladenosine (m
A) is the most abundant RNA modification in mammalian cells and the best-studied epitranscriptomic mark. Despite the development of various tools to map m
A, a transcriptome-wide method that enables absolute quantification of m
A at single-base resolution is lacking. Here we use glyoxal and nitrite-mediated deamina...
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Full title
Absolute quantification of single-base m 6 A methylation in the mammalian transcriptome using GLORI
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TN_cdi_pubmed_primary_36302990
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_36302990
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E-ISSN
1546-1696
DOI
10.1038/s41587-022-01487-9