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GZMK high CD8 + T effector memory cells are associated with CD15 high neutrophil abundance in non-me...

GZMK high CD8 + T effector memory cells are associated with CD15 high neutrophil abundance in non-me...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_36347862

GZMK high CD8 + T effector memory cells are associated with CD15 high neutrophil abundance in non-metastatic colorectal tumors and predict poor clinical outcome

About this item

Full title

GZMK high CD8 + T effector memory cells are associated with CD15 high neutrophil abundance in non-metastatic colorectal tumors and predict poor clinical outcome

Publisher

England

Journal title

Nature communications, 2022-11, Vol.13 (1), p.6752

Language

English

Formats

Publication information

Publisher

England

More information

Scope and Contents

Contents

CD8
T cells are a major prognostic determinant in solid tumors, including colorectal cancer (CRC). However, understanding how the interplay between different immune cells impacts on clinical outcome is still in its infancy. Here, we describe that the interaction of tumor infiltrating neutrophils expressing high levels of CD15 with CD8
T effec...

Alternative Titles

Full title

GZMK high CD8 + T effector memory cells are associated with CD15 high neutrophil abundance in non-metastatic colorectal tumors and predict poor clinical outcome

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmed_primary_36347862

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_36347862

Other Identifiers

E-ISSN

2041-1723

DOI

10.1038/s41467-022-34467-3

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