Structural basis of selective cannabinoid CB 2 receptor activation
Structural basis of selective cannabinoid CB 2 receptor activation
About this item
Full title
Author / Creator
Li, Xiaoting , Chang, Hao , Bouma, Jara , de Paus, Laura V , Mukhopadhyay, Partha , Paloczi, Janos , Mustafa, Mohammed , van der Horst, Cas , Kumar, Sanjay Sunil , Wu, Lijie , Yu, Yanan , van den Berg, Richard J B H N , Janssen, Antonius P A , Lichtman, Aron , Liu, Zhi-Jie , Pacher, Pal , van der Stelt, Mario , Heitman, Laura H and Hua, Tian
Publisher
England
Journal title
Language
English
Formats
Publication information
Publisher
England
Subjects
More information
Scope and Contents
Contents
Cannabinoid CB
receptor (CB
R) agonists are investigated as therapeutic agents in the clinic. However, their molecular mode-of-action is not fully understood. Here, we report the discovery of LEI-102, a CB
R agonist, used in conjunction with three other CBR ligands (APD371, HU308, and CP55,940) to investigate the selective CB
R activati...
Alternative Titles
Full title
Structural basis of selective cannabinoid CB 2 receptor activation
Authors, Artists and Contributors
Author / Creator
Chang, Hao
Bouma, Jara
de Paus, Laura V
Mukhopadhyay, Partha
Paloczi, Janos
Mustafa, Mohammed
van der Horst, Cas
Kumar, Sanjay Sunil
Wu, Lijie
Yu, Yanan
van den Berg, Richard J B H N
Janssen, Antonius P A
Lichtman, Aron
Liu, Zhi-Jie
Pacher, Pal
van der Stelt, Mario
Heitman, Laura H
Hua, Tian
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmed_primary_36922494
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_36922494
Other Identifiers
E-ISSN
2041-1723
DOI
10.1038/s41467-023-37112-9
