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Site-specific 68 Ga-labeled nanobody for PET imaging of CD70 expression in preclinical tumor models

Site-specific 68 Ga-labeled nanobody for PET imaging of CD70 expression in preclinical tumor models

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_37093350

Site-specific 68 Ga-labeled nanobody for PET imaging of CD70 expression in preclinical tumor models

About this item

Full title

Site-specific 68 Ga-labeled nanobody for PET imaging of CD70 expression in preclinical tumor models

Publisher

England

Journal title

EJNMMI radiopharmacy and chemistry, 2023-04, Vol.8 (1), p.8

Language

English

Formats

Publication information

Publisher

England

More information

Scope and Contents

Contents

CD70-CD27 is a costimulatory ligand-receptor pair in the tumor necrosis factor receptor family. With only limited expression in normal tissues, CD70 is constitutively expressed in a variety of solid tumors and hematologic malignancies, facilitating immunosuppression through CD27 signaling in the tumor microenvironment by enhanced survival of regula...

Alternative Titles

Full title

Site-specific 68 Ga-labeled nanobody for PET imaging of CD70 expression in preclinical tumor models

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmed_primary_37093350

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_37093350

Other Identifiers

E-ISSN

2365-421X

DOI

10.1186/s41181-023-00194-3

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