AraC interacts with p75 NTR transmembrane domain to induce cell death of mature neurons
AraC interacts with p75 NTR transmembrane domain to induce cell death of mature neurons
About this item
Full title
AraC interacts with p75 NTR transmembrane domain to induce cell death of mature neurons
Author / Creator
Publisher
England
Journal title
Cell death & disease, 2023-07, Vol.14 (7), p.440
Language
English
Formats
Publication information
Publisher
England
Subjects
More information
Scope and Contents
Contents
Cytosine arabinoside (AraC) is one of the main therapeutic treatments for several types of cancer, including acute myeloid leukaemia. However, after a high-dose AraC chemotherapy regime, patients develop severe neurotoxicity and cell death in the central nervous system leading to cerebellar ataxia, dysarthria, nystagmus, somnolence and drowsiness....
Alternative Titles
Full title
AraC interacts with p75 NTR transmembrane domain to induce cell death of mature neurons
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmed_primary_37460457
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_37460457
Other Identifiers
E-ISSN
2041-4889
DOI
10.1038/s41419-023-05979-7
