Cytidine Methylation of Regulatory Sequences Near the π-Class Glutathione S-Transferase Gene Accompa...
Cytidine Methylation of Regulatory Sequences Near the π-Class Glutathione S-Transferase Gene Accompanies Human Prostatic Carcinogenesis
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Full title
Author / Creator
Lee, W H , Morton, R A , Epstein, J I , Brooks, J D , Campbell, P A , Bova, G S , Hsieh, W S , Isaacs, W B and Nelson, W G
Publisher
United States: National Academy of Sciences of the United States of America
Journal title
Language
English
Formats
Publication information
Publisher
United States: National Academy of Sciences of the United States of America
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Scope and Contents
Contents
Hypermethylation of regulatory sequences at the locus of the π-class glutathione S-transferase gene GSTP1 was detected in 20 of 20 human prostatic carcinoma tissue specimens studied but not in normal tissues or prostatic tissues exhibiting benign hyperplasia. In addition, a striking decrease in GSTP1 expression was found to accompany human prostati...
Alternative Titles
Full title
Cytidine Methylation of Regulatory Sequences Near the π-Class Glutathione S-Transferase Gene Accompanies Human Prostatic Carcinogenesis
Authors, Artists and Contributors
Author / Creator
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Primary Identifiers
Record Identifier
TN_cdi_pubmed_primary_7972132
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_7972132
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.91.24.11733
