Prostate cancer reactivates developmental epigenomic programs during metastatic progression
Prostate cancer reactivates developmental epigenomic programs during metastatic progression
About this item
Full title
Author / Creator
Pomerantz, Mark M. , Qiu, Xintao , Zhu, Yanyun , Takeda, David Y. , Pan, Wenting , Baca, Sylvan C. , Gusev, Alexander , Korthauer, Keegan D. , Severson, Tesa M. , Ha, Gavin , Viswanathan, Srinivas R. , Seo, Ji-Heui , Nguyen, Holly M. , Zhang, Baohui , Pasaniuc, Bogdan , Giambartolomei, Claudia , Alaiwi, Sarah A. , Bell, Connor A. , O’Connor, Edward P. , Chabot, Matthew S. , Stillman, David R. , Lis, Rosina , Font-Tello, Alba , Li, Lewyn , Cejas, Paloma , Bergman, Andries M. , Sanders, Joyce , van der Poel, Henk G. , Gayther, Simon A. , Lawrenson, Kate , Fonseca, Marcos A. S. , Reddy, Jessica , Corona, Rosario I. , Martovetsky, Gleb , Egan, Brian , Choueiri, Toni , Ellis, Leigh , Garraway, Isla P. , Lee, Gwo-Shu Mary , Corey, Eva , Long, Henry W. , Zwart, Wilbert and Freedman, Matthew L.
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Epigenetic processes govern prostate cancer (PCa) biology, as evidenced by the dependency of PCa cells on the androgen receptor (AR), a prostate master transcription factor. We generated 268 epigenomic datasets spanning two state transitions—from normal prostate epithelium to localized PCa to metastases—in specimens derived from human tissue. We di...
Alternative Titles
Full title
Prostate cancer reactivates developmental epigenomic programs during metastatic progression
Authors, Artists and Contributors
Author / Creator
Qiu, Xintao
Zhu, Yanyun
Takeda, David Y.
Pan, Wenting
Baca, Sylvan C.
Gusev, Alexander
Korthauer, Keegan D.
Severson, Tesa M.
Ha, Gavin
Viswanathan, Srinivas R.
Seo, Ji-Heui
Nguyen, Holly M.
Zhang, Baohui
Pasaniuc, Bogdan
Giambartolomei, Claudia
Alaiwi, Sarah A.
Bell, Connor A.
O’Connor, Edward P.
Chabot, Matthew S.
Stillman, David R.
Lis, Rosina
Font-Tello, Alba
Li, Lewyn
Cejas, Paloma
Bergman, Andries M.
Sanders, Joyce
van der Poel, Henk G.
Gayther, Simon A.
Lawrenson, Kate
Fonseca, Marcos A. S.
Reddy, Jessica
Corona, Rosario I.
Martovetsky, Gleb
Egan, Brian
Choueiri, Toni
Ellis, Leigh
Garraway, Isla P.
Lee, Gwo-Shu Mary
Corey, Eva
Long, Henry W.
Zwart, Wilbert
Freedman, Matthew L.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10007911
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10007911
Other Identifiers
ISSN
1061-4036
E-ISSN
1546-1718
DOI
10.1038/s41588-020-0664-8
