Prevalence and Associations of Beta2-Microglobulin Mutations in MSI-H/dMMR Cancers
Prevalence and Associations of Beta2-Microglobulin Mutations in MSI-H/dMMR Cancers
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Author / Creator
Liu, Fangcen , Zhong, Fangfang , Wu, Huan , Che, Keying , Shi, Jiaochun , Wu, Nandie , Fu, Yao , Wang, Yue , Hu, Jing , Qian, Xiaoping , Fan, Xiangshan , Wang, Weifeng and Wei, Jia
Publisher
US: Oxford University Press
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Language
English
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US: Oxford University Press
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Abstract
Microsatellite instability (MSI) has emerged as an important predictor of sensitivity for immunotherapy-based strategies. β-2-Microglobulin (B2M) contains microsatellites within the coding regions and is prone to somatic changes in MSI/mismatch repair deficiency (MSI/dMMR) tumors. To delineate prevalence and associations of B2M mutation...
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Full title
Prevalence and Associations of Beta2-Microglobulin Mutations in MSI-H/dMMR Cancers
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10020813
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10020813
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ISSN
1083-7159
E-ISSN
1549-490X
DOI
10.1093/oncolo/oyac268