Preclinical models for prediction of immunotherapy outcomes and immune evasion mechanisms in genetic...
Preclinical models for prediction of immunotherapy outcomes and immune evasion mechanisms in genetically heterogeneous multiple myeloma
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Author / Creator
Larrayoz, Marta , Garcia-Barchino, Maria J. , Celay, Jon , Etxebeste, Amaia , Jimenez, Maddalen , Perez, Cristina , Ordoñez, Raquel , Cobaleda, Cesar , Botta, Cirino , Fresquet, Vicente , Roa, Sergio , Goicoechea, Ibai , Maia, Catarina , Lasaga, Miren , Chesi, Marta , Bergsagel, P. Leif , Larrayoz, Maria J. , Calasanz, Maria J. , Campos-Sanchez, Elena , Martinez-Cano, Jorge , Panizo, Carlos , Rodriguez-Otero, Paula , Vicent, Silvestre , Roncador, Giovanna , Gonzalez, Patricia , Takahashi, Satoru , Katz, Samuel G. , Walensky, Loren D. , Ruppert, Shannon M. , Lasater, Elisabeth A. , Amann, Maria , Lozano, Teresa , Llopiz, Diana , Sarobe, Pablo , Lasarte, Juan J. , Planell, Nuria , Gomez-Cabrero, David , Kudryashova, Olga , Kurilovich, Anna , Revuelta, Maria V. , Cerchietti, Leandro , Agirre, Xabier , San Miguel, Jesus , Paiva, Bruno , Prosper, Felipe and Martinez-Climent, Jose A.
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publication information
Publisher
New York: Nature Publishing Group US
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Scope and Contents
Contents
The historical lack of preclinical models reflecting the genetic heterogeneity of multiple myeloma (MM) hampers the advance of therapeutic discoveries. To circumvent this limitation, we screened mice engineered to carry eight MM lesions (NF-κB, KRAS, MYC, TP53, BCL2, cyclin D1, MMSET/NSD2 and c-MAF) combinatorially activated in B lymphocytes follow...
Alternative Titles
Full title
Preclinical models for prediction of immunotherapy outcomes and immune evasion mechanisms in genetically heterogeneous multiple myeloma
Authors, Artists and Contributors
Author / Creator
Garcia-Barchino, Maria J.
Celay, Jon
Etxebeste, Amaia
Jimenez, Maddalen
Perez, Cristina
Ordoñez, Raquel
Cobaleda, Cesar
Botta, Cirino
Fresquet, Vicente
Roa, Sergio
Goicoechea, Ibai
Maia, Catarina
Lasaga, Miren
Chesi, Marta
Bergsagel, P. Leif
Larrayoz, Maria J.
Calasanz, Maria J.
Campos-Sanchez, Elena
Martinez-Cano, Jorge
Panizo, Carlos
Rodriguez-Otero, Paula
Vicent, Silvestre
Roncador, Giovanna
Gonzalez, Patricia
Takahashi, Satoru
Katz, Samuel G.
Walensky, Loren D.
Ruppert, Shannon M.
Lasater, Elisabeth A.
Amann, Maria
Lozano, Teresa
Llopiz, Diana
Sarobe, Pablo
Lasarte, Juan J.
Planell, Nuria
Gomez-Cabrero, David
Kudryashova, Olga
Kurilovich, Anna
Revuelta, Maria V.
Cerchietti, Leandro
Agirre, Xabier
San Miguel, Jesus
Paiva, Bruno
Prosper, Felipe
Martinez-Climent, Jose A.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10033443
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10033443
Other Identifiers
ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/s41591-022-02178-3
