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Nucleotide metabolism: a pan-cancer metabolic dependency

Nucleotide metabolism: a pan-cancer metabolic dependency

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10041518

Nucleotide metabolism: a pan-cancer metabolic dependency

About this item

Full title

Nucleotide metabolism: a pan-cancer metabolic dependency

Publisher

London: Nature Publishing Group UK

Journal title

Nature reviews. Cancer, 2023-05, Vol.23 (5), p.275-294

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Metabolic alterations are a key hallmark of cancer cells, and the augmented synthesis and use of nucleotide triphosphates is a critical and universal metabolic dependency of cancer cells across different cancer types and genetic backgrounds. Many of the aggressive behaviours of cancer cells, including uncontrolled proliferation, chemotherapy resist...

Alternative Titles

Full title

Nucleotide metabolism: a pan-cancer metabolic dependency

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10041518

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10041518

Other Identifiers

ISSN

1474-175X,1474-1768

E-ISSN

1474-1768

DOI

10.1038/s41568-023-00557-7

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