Neurodegenerative Changes in the Brains of the 5xFAD Alzheimer's Disease Model Mice Investigated by...
Neurodegenerative Changes in the Brains of the 5xFAD Alzheimer's Disease Model Mice Investigated by High-Field and High-Resolution Magnetic Resonance Imaging and Multi-Nuclei Magnetic Resonance Spectroscopy
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Publisher
Switzerland: MDPI AG
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Language
English
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Switzerland: MDPI AG
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This study aimed to investigate morphological and metabolic changes in the brains of 5xFAD mice. Structural magnetic resonance imaging (MRI) and
H magnetic resonance spectroscopy (MRS) were obtained in 10- and 14-month-old 5xFAD and wild-type (WT) mice, while
P MRS scans were acquired in 11-month-old mice. Significantly reduced gray matter (G...
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Full title
Neurodegenerative Changes in the Brains of the 5xFAD Alzheimer's Disease Model Mice Investigated by High-Field and High-Resolution Magnetic Resonance Imaging and Multi-Nuclei Magnetic Resonance Spectroscopy
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10049146
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10049146
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ISSN
1422-0067,1661-6596
E-ISSN
1422-0067
DOI
10.3390/ijms24065073