Trop-2 and Nectin-4 immunohistochemical expression in metastatic colorectal cancer: searching for th...
Trop-2 and Nectin-4 immunohistochemical expression in metastatic colorectal cancer: searching for the right population for drugs’ development
About this item
Full title
Author / Creator
Moretto, Roberto , Germani, Marco Maria , Giordano, Mirella , Conca, Veronica , Proietti, Agnese , Niccoli, Cristina , Pietrantonio, Filippo , Lonardi, Sara , Tamburini, Emiliano , Zaniboni, Alberto , Passardi, Alessandro , Latiano, Tiziana Pia , Fanotto, Valentina , Di Donato, Samantha , Prisciandaro, Michele , Bergamo, Francesca , Masi, Gianluca , Fontanini, Gabriella , Ugolini, Clara and Cremolini, Chiara
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Background
Trop-2 and Nectin-4 are transmembrane proteins overexpressed in many tumours and targets of antibody–drug conjugates (ADC). In metastatic colorectal cancer (mCRC), the role of Trop-2 and Nectin-4 has been poorly investigated.
Methods
Tumour samples of patients randomised in the phase III TRIBE2 were assessed for Trop-2 and Necti...
Alternative Titles
Full title
Trop-2 and Nectin-4 immunohistochemical expression in metastatic colorectal cancer: searching for the right population for drugs’ development
Authors, Artists and Contributors
Author / Creator
Germani, Marco Maria
Giordano, Mirella
Conca, Veronica
Proietti, Agnese
Niccoli, Cristina
Pietrantonio, Filippo
Lonardi, Sara
Tamburini, Emiliano
Zaniboni, Alberto
Passardi, Alessandro
Latiano, Tiziana Pia
Fanotto, Valentina
Di Donato, Samantha
Prisciandaro, Michele
Bergamo, Francesca
Masi, Gianluca
Fontanini, Gabriella
Ugolini, Clara
Cremolini, Chiara
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10049995
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10049995
Other Identifiers
ISSN
0007-0920
E-ISSN
1532-1827
DOI
10.1038/s41416-023-02180-7
