Androgen receptor blockade promotes response to BRAF/MEK-targeted therapy
Androgen receptor blockade promotes response to BRAF/MEK-targeted therapy
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Author / Creator
Vellano, Christopher P. , White, Michael G. , Andrews, Miles C. , Chelvanambi, Manoj , Witt, Russell G. , Daniele, Joseph R. , Titus, Mark , McQuade, Jennifer L. , Conforti, Fabio , Burton, Elizabeth M. , Lastrapes, Matthew J. , Ologun, Gabriel , Cogdill, Alexandria P. , Morad, Golnaz , Prieto, Peter , Lazar, Alexander J. , Chu, Yanshuo , Han, Guangchun , Khan, M. A. Wadud , Helmink, Beth , Davies, Michael A. , Amaria, Rodabe N. , Kovacs, Jeffrey J. , Woodman, Scott E. , Patel, Sapna , Hwu, Patrick , Peoples, Michael , Lee, Jeffrey E. , Cooper, Zachary A. , Zhu, Haifeng , Gao, Guang , Banerjee, Hiya , Lau, Mike , Gershenwald, Jeffrey E. , Lucci, Anthony , Keung, Emily Z. , Ross, Merrick I. , Pala, Laura , Pagan, Eleonora , Segura, Rossana Lazcano , Liu, Qian , Borthwick, Mikayla S. , Lau, Eric , Yates, Melinda S. , Westin, Shannon N. , Wani, Khalida , Tetzlaff, Michael T. , Haydu, Lauren E. , Mahendra, Mikhila , Ma, XiaoYan , Logothetis, Christopher , Kulstad, Zachary , Johnson, Sarah , Hudgens, Courtney W. , Feng, Ningping , Federico, Lorenzo , Long, Georgina V. , Futreal, P. Andrew , Arur, Swathi , Tawbi, Hussein A. , Moran, Amy E. , Wang, Linghua , Heffernan, Timothy P. , Marszalek, Joseph R. and Wargo, Jennifer A.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Treatment with therapy targeting BRAF and MEK (BRAF/MEK) has revolutionized care in melanoma and other cancers; however, therapeutic resistance is common and innovative treatment strategies are needed
1
,
2
. Here we studied a group of patients with melanoma who were treated with neoadjuvant BRAF/MEK-targeted therapy (
NCT02231775
Alternative Titles
Full title
Androgen receptor blockade promotes response to BRAF/MEK-targeted therapy
Authors, Artists and Contributors
Author / Creator
White, Michael G.
Andrews, Miles C.
Chelvanambi, Manoj
Witt, Russell G.
Daniele, Joseph R.
Titus, Mark
McQuade, Jennifer L.
Conforti, Fabio
Burton, Elizabeth M.
Lastrapes, Matthew J.
Ologun, Gabriel
Cogdill, Alexandria P.
Morad, Golnaz
Prieto, Peter
Lazar, Alexander J.
Chu, Yanshuo
Han, Guangchun
Khan, M. A. Wadud
Helmink, Beth
Davies, Michael A.
Amaria, Rodabe N.
Kovacs, Jeffrey J.
Woodman, Scott E.
Patel, Sapna
Hwu, Patrick
Peoples, Michael
Lee, Jeffrey E.
Cooper, Zachary A.
Zhu, Haifeng
Gao, Guang
Banerjee, Hiya
Lau, Mike
Gershenwald, Jeffrey E.
Lucci, Anthony
Keung, Emily Z.
Ross, Merrick I.
Pala, Laura
Pagan, Eleonora
Segura, Rossana Lazcano
Liu, Qian
Borthwick, Mikayla S.
Lau, Eric
Yates, Melinda S.
Westin, Shannon N.
Wani, Khalida
Tetzlaff, Michael T.
Haydu, Lauren E.
Mahendra, Mikhila
Ma, XiaoYan
Logothetis, Christopher
Kulstad, Zachary
Johnson, Sarah
Hudgens, Courtney W.
Feng, Ningping
Federico, Lorenzo
Long, Georgina V.
Futreal, P. Andrew
Arur, Swathi
Tawbi, Hussein A.
Moran, Amy E.
Wang, Linghua
Heffernan, Timothy P.
Marszalek, Joseph R.
Wargo, Jennifer A.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10071594
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10071594
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-022-04833-8
