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Urinary tract infections trigger synucleinopathy via the innate immune response

Urinary tract infections trigger synucleinopathy via the innate immune response

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10119259

Urinary tract infections trigger synucleinopathy via the innate immune response

Publication information

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

More information

Scope and Contents

Contents

Symptoms in the urogenital organs are common in multiple system atrophy (MSA), also in the years preceding the MSA diagnosis. It is unknown how MSA is triggered and these observations in prodromal MSA led us to hypothesize that synucleinopathy could be triggered by infection of the genitourinary tract causing ɑ-synuclein (ɑSyn) to aggregate in peri...

Alternative Titles

Full title

Urinary tract infections trigger synucleinopathy via the innate immune response

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10119259

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10119259

Other Identifiers

ISSN

0001-6322,1432-0533

E-ISSN

1432-0533

DOI

10.1007/s00401-023-02562-4

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