An IL1RL1 genetic variant lowers soluble ST2 levels and the risk effects of APOE-ε4 in female patien...
An IL1RL1 genetic variant lowers soluble ST2 levels and the risk effects of APOE-ε4 in female patients with Alzheimer’s disease
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Author / Creator
Alzheimer’s Disease Neuroimaging Initiative , Jiang, Yuanbing , Zhou, Xiaopu , Wong, Hiu Yi , Ouyang, Li , Ip, Fanny C. F. , Chau, Vicky M. N. , Lau, Shun-Fat , Wu, Wei , Wong, Daniel Y. K. , Seo, Heukjin , Fu, Wing-Yu , Lai, Nicole C. H. , Chen, Yuewen , Chen, Yu , Tong, Estella P. S. , Weiner, Michael W. , Aisen, Paul , Petersen, Ronald , Jack, Clifford R. , Jagust, William , Trojanowski, John Q. , Toga, Arthur W. , Beckett, Laurel , Green, Robert C. , Saykin, Andrew J. , Morris, John , Shaw, Leslie M. , Khachaturian, Zaven , Sorensen, Greg , Kuller, Lew , Raichle, Marcus , Paul, Steven , Davies, Peter , Fillit, Howard , Hefti, Franz , Holtzman, David , Mesulam, Marek M. , Potter, William , Snyder, Peter , Schwartz, Adam , Montine, Tom , Thomas, Ronald G. , Donohue, Michael , Walter, Sarah , Gessert, Devon , Sather, Tamie , Jiminez, Gus , Harvey, Danielle , Bernstein, Matthew , Thompson, Paul , Schuff, Norbert , Borowski, Bret , Gunter, Jeff , Senjem, Matt , Vemuri, Prashanthi , Jones, David , Kantarci, Kejal , Ward, Chad , Koeppe, Robert A. , Foster, Norm , Reiman, Eric M. , Chen, Kewei , Mathis, Chet , Landau, Susan , Cairns, Nigel J. , Householder, Erin , Taylor-Reinwald, Lisa , Lee, Virginia , Korecka, Magdalena , Figurski, Michal , Crawford, Karen , Neu, Scott , Foroud, Tatiana M. , Potkin, Steven G. , Shen, Li , Faber, Kelley , Kim, Sungeun , Nho, Kwangsik , Thal, Leon , Buckholtz, Neil , Albert, Marylyn , Frank, Richard , Hsiao, John , Kaye, Jeffrey , Quinn, Joseph , Lind, Betty , Carter, Raina , Dolen, Sara , Schneider, Lon S. , Pawluczyk, Sonia , Beccera, Mauricio , Teodoro, Liberty , Spann, Bryan M. , Brewer, James , Vanderswag, Helen , Fleisher, Adam , Heidebrink, Judith L. , Lord, Joanne L. , Mason, Sara S. and Albers, Colleen S.
Publisher
United States: Nature Publishing Group
Journal title
Language
English
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Publisher
United States: Nature Publishing Group
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Scope and Contents
Contents
Changes in the levels of circulating proteins are associated with Alzheimer’s disease (AD), whereas their pathogenic roles in AD are unclear. Here, we identified soluble ST2 (sST2), a decoy receptor of interleukin-33–ST2 signaling, as a new disease-causing factor in AD. Increased circulating sST2 level is associated with more severe pathological ch...
Alternative Titles
Full title
An IL1RL1 genetic variant lowers soluble ST2 levels and the risk effects of APOE-ε4 in female patients with Alzheimer’s disease
Authors, Artists and Contributors
Author / Creator
Jiang, Yuanbing
Zhou, Xiaopu
Wong, Hiu Yi
Ouyang, Li
Ip, Fanny C. F.
Chau, Vicky M. N.
Lau, Shun-Fat
Wu, Wei
Wong, Daniel Y. K.
Seo, Heukjin
Fu, Wing-Yu
Lai, Nicole C. H.
Chen, Yuewen
Chen, Yu
Tong, Estella P. S.
Weiner, Michael W.
Aisen, Paul
Petersen, Ronald
Jack, Clifford R.
Jagust, William
Trojanowski, John Q.
Toga, Arthur W.
Beckett, Laurel
Green, Robert C.
Saykin, Andrew J.
Morris, John
Shaw, Leslie M.
Khachaturian, Zaven
Sorensen, Greg
Kuller, Lew
Raichle, Marcus
Paul, Steven
Davies, Peter
Fillit, Howard
Hefti, Franz
Holtzman, David
Mesulam, Marek M.
Potter, William
Snyder, Peter
Schwartz, Adam
Montine, Tom
Thomas, Ronald G.
Donohue, Michael
Walter, Sarah
Gessert, Devon
Sather, Tamie
Jiminez, Gus
Harvey, Danielle
Bernstein, Matthew
Thompson, Paul
Schuff, Norbert
Borowski, Bret
Gunter, Jeff
Senjem, Matt
Vemuri, Prashanthi
Jones, David
Kantarci, Kejal
Ward, Chad
Koeppe, Robert A.
Foster, Norm
Reiman, Eric M.
Chen, Kewei
Mathis, Chet
Landau, Susan
Cairns, Nigel J.
Householder, Erin
Taylor-Reinwald, Lisa
Lee, Virginia
Korecka, Magdalena
Figurski, Michal
Crawford, Karen
Neu, Scott
Foroud, Tatiana M.
Potkin, Steven G.
Shen, Li
Faber, Kelley
Kim, Sungeun
Nho, Kwangsik
Thal, Leon
Buckholtz, Neil
Albert, Marylyn
Frank, Richard
Hsiao, John
Kaye, Jeffrey
Quinn, Joseph
Lind, Betty
Carter, Raina
Dolen, Sara
Schneider, Lon S.
Pawluczyk, Sonia
Beccera, Mauricio
Teodoro, Liberty
Spann, Bryan M.
Brewer, James
Vanderswag, Helen
Fleisher, Adam
Heidebrink, Judith L.
Lord, Joanne L.
Mason, Sara S.
Albers, Colleen S.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10154240
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10154240
Other Identifiers
ISSN
2662-8465
E-ISSN
2662-8465
DOI
10.1038/s43587-022-00241-9
