Systemic kappa opioid receptor antagonism accelerates reinforcement learning via augmentation of nov...
Systemic kappa opioid receptor antagonism accelerates reinforcement learning via augmentation of novelty processing in male mice
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England: Nature Publishing Group
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English
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England: Nature Publishing Group
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Selective inhibition of kappa opioid receptors (KORs) is highly anticipated as a pharmacotherapeutic intervention for substance use disorders and depression. The accepted explanation for KOR antagonist-induced amelioration of aberrant behaviors posits that KORs globally function as a negative valence system; antagonism thereby blunts the behavioral...
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Systemic kappa opioid receptor antagonism accelerates reinforcement learning via augmentation of novelty processing in male mice
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10156709
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10156709
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0893-133X,1740-634X
E-ISSN
1740-634X
DOI
10.1038/s41386-023-01547-x