Accelerated RNA detection using tandem CRISPR nucleases
Accelerated RNA detection using tandem CRISPR nucleases
About this item
Full title
Author / Creator
IGI Testing Consortium , Liu, Tina Y. , Knott, Gavin J. , Smock, Dylan C. J. , Desmarais, John J. , Son, Sungmin , Bhuiya, Abdul , Jakhanwal, Shrutee , Prywes, Noam , Agrawal, Shreeya , Díaz de León Derby, María , Switz, Neil A. , Armstrong, Maxim , Harris, Andrew R. , Charles, Emeric J. , Thornton, Brittney W. , Fozouni, Parinaz , Shu, Jeffrey , Stephens, Stephanie I. , Kumar, G. Renuka , Zhao, Chunyu , Mok, Amanda , Iavarone, Anthony T. , Escajeda, Arturo M. , McIntosh, Roger , Kim, Shineui , Dugan, Eli J. , Pollard, Katherine S. , Tan, Ming X. , Ott, Melanie , Fletcher, Daniel A. , Lareau, Liana F. , Hsu, Patrick D. , Savage, David F. and Doudna, Jennifer A.
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Direct, amplification-free detection of RNA has the potential to transform molecular diagnostics by enabling simple on-site analysis of human or environmental samples. CRISPR–Cas nucleases offer programmable RNA-guided RNA recognition that triggers cleavage and release of a fluorescent reporter molecule, but long reaction times hamper their detecti...
Alternative Titles
Full title
Accelerated RNA detection using tandem CRISPR nucleases
Authors, Artists and Contributors
Author / Creator
Liu, Tina Y.
Knott, Gavin J.
Smock, Dylan C. J.
Desmarais, John J.
Son, Sungmin
Bhuiya, Abdul
Jakhanwal, Shrutee
Prywes, Noam
Agrawal, Shreeya
Díaz de León Derby, María
Switz, Neil A.
Armstrong, Maxim
Harris, Andrew R.
Charles, Emeric J.
Thornton, Brittney W.
Fozouni, Parinaz
Shu, Jeffrey
Stephens, Stephanie I.
Kumar, G. Renuka
Zhao, Chunyu
Mok, Amanda
Iavarone, Anthony T.
Escajeda, Arturo M.
McIntosh, Roger
Kim, Shineui
Dugan, Eli J.
Pollard, Katherine S.
Tan, Ming X.
Ott, Melanie
Fletcher, Daniel A.
Lareau, Liana F.
Hsu, Patrick D.
Savage, David F.
Doudna, Jennifer A.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10184463
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10184463
Other Identifiers
ISSN
1552-4450
E-ISSN
1552-4469
DOI
10.1038/s41589-021-00842-2
