IFNγ-induction of TH1-like regulatory T cells controls antiviral responses
IFNγ-induction of TH1-like regulatory T cells controls antiviral responses
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Author / Creator
Gocher-Demske, Angela M. , Cui, Jian , Szymczak-Workman, Andrea L. , Vignali, Kate M. , Latini, Julianna N. , Pieklo, Gwen P. , Kimball, Jesse C. , Avery, Lyndsay , Cipolla, Ellyse M. , Huckestein, Brydie R. , Hedden, Lee , Meisel, Marlies , Alcorn, John F. , Kane, Lawrence P. , Workman, Creg J. and Vignali, Dario A. A.
Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Scope and Contents
Contents
Regulatory T (T
reg
) cells are an immunosuppressive population that are required to maintain peripheral tolerance and prevent tissue damage from immunopathology, via anti-inflammatory cytokines, inhibitor receptors and metabolic disruption. Here we show that T
reg
cells acquire an effector-like state, yet remain stable and functional,...
Alternative Titles
Full title
IFNγ-induction of TH1-like regulatory T cells controls antiviral responses
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10224582
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10224582
Other Identifiers
ISSN
1529-2908,1529-2916
E-ISSN
1529-2916
DOI
10.1038/s41590-023-01453-w