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Dynamic mitochondrial transcription and translation in B cells control germinal center entry and lym...

Dynamic mitochondrial transcription and translation in B cells control germinal center entry and lym...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10232359

Dynamic mitochondrial transcription and translation in B cells control germinal center entry and lymphomagenesis

About this item

Full title

Dynamic mitochondrial transcription and translation in B cells control germinal center entry and lymphomagenesis

Publisher

New York: Nature Publishing Group US

Journal title

Nature immunology, 2023-06, Vol.24 (6), p.991-1006

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Germinal center (GC) B cells undergo proliferation at very high rates in a hypoxic microenvironment but the cellular processes driving this are incompletely understood. Here we show that the mitochondria of GC B cells are highly dynamic, with significantly upregulated transcription and translation rates associated with the activity of transcription...

Alternative Titles

Full title

Dynamic mitochondrial transcription and translation in B cells control germinal center entry and lymphomagenesis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10232359

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10232359

Other Identifiers

ISSN

1529-2908

E-ISSN

1529-2916

DOI

10.1038/s41590-023-01484-3

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