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Single targeting of MET in EGFR-mutated and MET-amplified non-small cell lung cancer

Single targeting of MET in EGFR-mutated and MET-amplified non-small cell lung cancer

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10241937

Single targeting of MET in EGFR-mutated and MET-amplified non-small cell lung cancer

About this item

Full title

Single targeting of MET in EGFR-mutated and MET-amplified non-small cell lung cancer

Publisher

London: Nature Publishing Group UK

Journal title

British journal of cancer, 2023-06, Vol.128 (12), p.2186-2196

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Background
In
EGFR
-mutant and
MET
-amplified lung cancer resistant to EGFR inhibitors, double blockade of EGFR and MET is considered as a reasonable strategy despite increasing toxicity. This study evaluated the single MET inhibition in these specific tumours.
Methods
We investigated the efficacy of a single MET inhibitor in

Alternative Titles

Full title

Single targeting of MET in EGFR-mutated and MET-amplified non-small cell lung cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10241937

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10241937

Other Identifiers

ISSN

0007-0920

E-ISSN

1532-1827

DOI

10.1038/s41416-023-02264-4

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