Log in to save to my catalogue

Evidence of nerve agent VX exposure in rat plasma by detection of albumin-adducts in vitro and in vi...

Evidence of nerve agent VX exposure in rat plasma by detection of albumin-adducts in vitro and in vi...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10256656

Evidence of nerve agent VX exposure in rat plasma by detection of albumin-adducts in vitro and in vivo

About this item

Full title

Evidence of nerve agent VX exposure in rat plasma by detection of albumin-adducts in vitro and in vivo

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

Journal title

Archives of toxicology, 2023-07, Vol.97 (7), p.1873-1885

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

More information

Scope and Contents

Contents

VX is a highly toxic organophosphorus nerve agent that reacts with a variety of endogenous proteins such as serum albumin under formation of adducts that can be targeted by analytical methods for biomedical verification of exposure. Albumin is phosphonylated by the ethyl methylphosphonic acid moiety (
EMP
) of VX at various tyrosine residues....

Alternative Titles

Full title

Evidence of nerve agent VX exposure in rat plasma by detection of albumin-adducts in vitro and in vivo

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10256656

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10256656

Other Identifiers

ISSN

0340-5761

E-ISSN

1432-0738

DOI

10.1007/s00204-023-03521-4

How to access this item