Enhancing untargeted metabolomics using metadata-based source annotation
Enhancing untargeted metabolomics using metadata-based source annotation
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Full title
Author / Creator
Gauglitz, Julia M. , West, Kiana A. , Bittremieux, Wout , Williams, Candace L. , Weldon, Kelly C. , Panitchpakdi, Morgan , Di Ottavio, Francesca , Aceves, Christine M. , Brown, Elizabeth , Sikora, Nicole C. , Jarmusch, Alan K. , Martino, Cameron , Tripathi, Anupriya , Meehan, Michael J. , Dorrestein, Kathleen , Shaffer, Justin P. , Coras, Roxana , Vargas, Fernando , Goldasich, Lindsay DeRight , Schwartz, Tara , Bryant, MacKenzie , Humphrey, Gregory , Johnson, Abigail J. , Spengler, Katharina , Belda-Ferre, Pedro , Diaz, Edgar , McDonald, Daniel , Zhu, Qiyun , Elijah, Emmanuel O. , Wang, Mingxun , Marotz, Clarisse , Sprecher, Kate E. , Vargas-Robles, Daniela , Withrow, Dana , Ackermann, Gail , Herrera, Lourdes , Bradford, Barry J. , Marques, Lucas Maciel Mauriz , Amaral, Juliano Geraldo , Silva, Rodrigo Moreira , Veras, Flavio Protasio , Cunha, Thiago Mattar , Oliveira, Rene Donizeti Ribeiro , Louzada-Junior, Paulo , Mills, Robert H. , Piotrowski, Paulina K. , Servetas, Stephanie L. , Da Silva, Sandra M. , Jones, Christina M. , Lin, Nancy J. , Lippa, Katrice A. , Jackson, Scott A. , Daouk, Rima Kaddurah , Galasko, Douglas , Dulai, Parambir S. , Kalashnikova, Tatyana I. , Wittenberg, Curt , Terkeltaub, Robert , Doty, Megan M. , Kim, Jae H. , Rhee, Kyung E. , Beauchamp-Walters, Julia , Wright, Kenneth P. , Dominguez-Bello, Maria Gloria , Manary, Mark , Oliveira, Michelli F. , Boland, Brigid S. , Lopes, Norberto Peporine , Guma, Monica , Swafford, Austin D. , Dutton, Rachel J. , Knight, Rob and Dorrestein, Pieter C.
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Human untargeted metabolomics studies annotate only ~10% of molecular features. We introduce reference-data-driven analysis to match metabolomics tandem mass spectrometry (MS/MS) data against metadata-annotated source data as a pseudo-MS/MS reference library. Applying this approach to food source data, we show that it increases MS/MS spectral usage...
Alternative Titles
Full title
Enhancing untargeted metabolomics using metadata-based source annotation
Authors, Artists and Contributors
Author / Creator
West, Kiana A.
Bittremieux, Wout
Williams, Candace L.
Weldon, Kelly C.
Panitchpakdi, Morgan
Di Ottavio, Francesca
Aceves, Christine M.
Brown, Elizabeth
Sikora, Nicole C.
Jarmusch, Alan K.
Martino, Cameron
Tripathi, Anupriya
Meehan, Michael J.
Dorrestein, Kathleen
Shaffer, Justin P.
Coras, Roxana
Vargas, Fernando
Goldasich, Lindsay DeRight
Schwartz, Tara
Bryant, MacKenzie
Humphrey, Gregory
Johnson, Abigail J.
Spengler, Katharina
Belda-Ferre, Pedro
Diaz, Edgar
McDonald, Daniel
Zhu, Qiyun
Elijah, Emmanuel O.
Wang, Mingxun
Marotz, Clarisse
Sprecher, Kate E.
Vargas-Robles, Daniela
Withrow, Dana
Ackermann, Gail
Herrera, Lourdes
Bradford, Barry J.
Marques, Lucas Maciel Mauriz
Amaral, Juliano Geraldo
Silva, Rodrigo Moreira
Veras, Flavio Protasio
Cunha, Thiago Mattar
Oliveira, Rene Donizeti Ribeiro
Louzada-Junior, Paulo
Mills, Robert H.
Piotrowski, Paulina K.
Servetas, Stephanie L.
Da Silva, Sandra M.
Jones, Christina M.
Lin, Nancy J.
Lippa, Katrice A.
Jackson, Scott A.
Daouk, Rima Kaddurah
Galasko, Douglas
Dulai, Parambir S.
Kalashnikova, Tatyana I.
Wittenberg, Curt
Terkeltaub, Robert
Doty, Megan M.
Kim, Jae H.
Rhee, Kyung E.
Beauchamp-Walters, Julia
Wright, Kenneth P.
Dominguez-Bello, Maria Gloria
Manary, Mark
Oliveira, Michelli F.
Boland, Brigid S.
Lopes, Norberto Peporine
Guma, Monica
Swafford, Austin D.
Dutton, Rachel J.
Knight, Rob
Dorrestein, Pieter C.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10277029
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10277029
Other Identifiers
ISSN
1087-0156,1546-1696
E-ISSN
1546-1696
DOI
10.1038/s41587-022-01368-1
