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Propagative α-synuclein seeds as serum biomarkers for synucleinopathies

Propagative α-synuclein seeds as serum biomarkers for synucleinopathies

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10287557

Propagative α-synuclein seeds as serum biomarkers for synucleinopathies

About this item

Full title

Propagative α-synuclein seeds as serum biomarkers for synucleinopathies

Publisher

New York: Nature Publishing Group US

Journal title

Nature medicine, 2023-06, Vol.29 (6), p.1448-1455

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Abnormal α-synuclein aggregation is a key pathological feature of a group of neurodegenerative diseases known as synucleinopathies, which include Parkinson’s disease (PD), dementia with Lewy bodies and multiple system atrophy (MSA). The pathogenic β-sheet seed conformation of α-synuclein is found in various tissues, suggesting potential as a biomar...

Alternative Titles

Full title

Propagative α-synuclein seeds as serum biomarkers for synucleinopathies

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10287557

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10287557

Other Identifiers

ISSN

1078-8956,1546-170X

E-ISSN

1546-170X

DOI

10.1038/s41591-023-02358-9

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