Curcumin activates a ROS/KEAP1/NRF2/miR-34a/b/c cascade to suppress colorectal cancer metastasis
Curcumin activates a ROS/KEAP1/NRF2/miR-34a/b/c cascade to suppress colorectal cancer metastasis
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Curcumin, a natural phytochemical isolated from tumeric roots, represents a candidate for prevention and therapy of colorectal cancer/CRC. However, the exact mechanism of action and the downstream mediators of curcumin’s tumor suppressive effects have remained largely unknown. Here we used a genetic approach to determine the role of the p53/miR-34...
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Curcumin activates a ROS/KEAP1/NRF2/miR-34a/b/c cascade to suppress colorectal cancer metastasis
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10307888
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10307888
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ISSN
1350-9047
E-ISSN
1476-5403
DOI
10.1038/s41418-023-01178-1
