Log in to save to my catalogue

Nutrient deprivation and hypoxia alter T cell immune checkpoint expression: potential impact for imm...

Nutrient deprivation and hypoxia alter T cell immune checkpoint expression: potential impact for imm...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10349772

Nutrient deprivation and hypoxia alter T cell immune checkpoint expression: potential impact for immunotherapy

About this item

Full title

Nutrient deprivation and hypoxia alter T cell immune checkpoint expression: potential impact for immunotherapy

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

Journal title

Journal of cancer research and clinical oncology, 2023-07, Vol.149 (8), p.5377-5395

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

More information

Scope and Contents

Contents

Aim
Use of immune checkpoint blockade to enhance T cell-mediated immunity within the hostile tumour microenvironment (TME) is an attractive approach in oesophageal adenocarcinoma (OAC). This study explored the effects of the hostile TME, including nutrient deprivation and hypoxia, on immune checkpoint (IC) expression and T cell phenotypes, and t...

Alternative Titles

Full title

Nutrient deprivation and hypoxia alter T cell immune checkpoint expression: potential impact for immunotherapy

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10349772

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10349772

Other Identifiers

ISSN

0171-5216

E-ISSN

1432-1335

DOI

10.1007/s00432-022-04440-0

How to access this item