TDP-43 forms amyloid filaments with a distinct fold in type A FTLD-TDP
TDP-43 forms amyloid filaments with a distinct fold in type A FTLD-TDP
About this item
Full title
Author / Creator
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
The abnormal assembly of TAR DNA-binding protein 43 (TDP-43) in neuronal and glial cells characterizes nearly all cases of amyotrophic lateral sclerosis (ALS) and around half of cases of frontotemporal lobar degeneration (FTLD)
1
,
2
. A causal role for TDP-43 assembly in neurodegeneration is evidenced by dominantly inherited missense m...
Alternative Titles
Full title
TDP-43 forms amyloid filaments with a distinct fold in type A FTLD-TDP
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10447236
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10447236
Other Identifiers
ISSN
0028-0836,1476-4687
E-ISSN
1476-4687
DOI
10.1038/s41586-023-06405-w
