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Transgenic mice overexpressing human ALOX15 under the control of the aP2 promoter are partly protect...

Transgenic mice overexpressing human ALOX15 under the control of the aP2 promoter are partly protect...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10499711

Transgenic mice overexpressing human ALOX15 under the control of the aP2 promoter are partly protected in the complete Freund’s adjuvant-induced paw inflammation model

About this item

Full title

Transgenic mice overexpressing human ALOX15 under the control of the aP2 promoter are partly protected in the complete Freund’s adjuvant-induced paw inflammation model

Publisher

Cham: Springer International Publishing

Journal title

Inflammation research, 2023-08, Vol.72 (8), p.1649-1664

Language

English

Formats

Publication information

Publisher

Cham: Springer International Publishing

More information

Scope and Contents

Contents

Background, objectives and design
Arachidonic acid 15-lipoxygenase (ALOX15) has been implicated in the pathogenesis of inflammatory diseases but since pro- and anti-inflammatory roles have been suggested, the precise function of this enzyme is still a matter of discussion. To contribute to this discussion, we created transgenic mice, which expre...

Alternative Titles

Full title

Transgenic mice overexpressing human ALOX15 under the control of the aP2 promoter are partly protected in the complete Freund’s adjuvant-induced paw inflammation model

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10499711

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10499711

Other Identifiers

ISSN

1023-3830,1420-908X

E-ISSN

1420-908X

DOI

10.1007/s00011-023-01770-8

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