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A positive feedback loop controls Toxoplasma chronic differentiation

A positive feedback loop controls Toxoplasma chronic differentiation

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10520893

A positive feedback loop controls Toxoplasma chronic differentiation

About this item

Full title

A positive feedback loop controls Toxoplasma chronic differentiation

Publisher

London: Nature Publishing Group UK

Journal title

Nature microbiology, 2023-05, Vol.8 (5), p.889-904

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Successful infection strategies must balance pathogen amplification and persistence. In the obligate intracellular parasite
Toxoplasma gondii
this is accomplished through differentiation into dedicated cyst-forming chronic stages that avoid clearance by the host immune system. The transcription factor BFD1 is both necessary and sufficient for...

Alternative Titles

Full title

A positive feedback loop controls Toxoplasma chronic differentiation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10520893

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10520893

Other Identifiers

ISSN

2058-5276

E-ISSN

2058-5276

DOI

10.1038/s41564-023-01358-2

How to access this item