A positive feedback loop controls Toxoplasma chronic differentiation
A positive feedback loop controls Toxoplasma chronic differentiation
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Successful infection strategies must balance pathogen amplification and persistence. In the obligate intracellular parasite
Toxoplasma gondii
this is accomplished through differentiation into dedicated cyst-forming chronic stages that avoid clearance by the host immune system. The transcription factor BFD1 is both necessary and sufficient for...
Alternative Titles
Full title
A positive feedback loop controls Toxoplasma chronic differentiation
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10520893
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10520893
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ISSN
2058-5276
E-ISSN
2058-5276
DOI
10.1038/s41564-023-01358-2