Histone demethylase KDM5D upregulation drives sex differences in colon cancer
Histone demethylase KDM5D upregulation drives sex differences in colon cancer
About this item
Full title
Author / Creator
Li, Jiexi , Lan, Zhengdao , Liao, Wenting , Horner, James W. , Xu, Xueping , Liu, Jielin , Yoshihama, Yohei , Jiang, Shan , Shim, Hong Seok , Slotnik, Max , LaBella, Kyle A. , Wu, Chang-Jiun , Dunner, Kenneth , Hsu, Wen-Hao , Lee, Rumi , Khanduri, Isha , Terranova, Christopher , Akdemir, Kadir , Chakravarti, Deepavali , Shang, Xiaoying , Spring, Denise J. , Wang, Y. Alan and DePinho, Ronald A.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Sex exerts a profound impact on cancer incidence, spectrum and outcomes, yet the molecular and genetic bases of such sex differences are ill-defined and presumptively ascribed to X-chromosome genes and sex hormones
1
. Such sex differences are particularly prominent in colorectal cancer (CRC) in which men experience higher metastases and mort...
Alternative Titles
Full title
Histone demethylase KDM5D upregulation drives sex differences in colon cancer
Authors, Artists and Contributors
Author / Creator
Lan, Zhengdao
Liao, Wenting
Horner, James W.
Xu, Xueping
Liu, Jielin
Yoshihama, Yohei
Jiang, Shan
Shim, Hong Seok
Slotnik, Max
LaBella, Kyle A.
Wu, Chang-Jiun
Dunner, Kenneth
Hsu, Wen-Hao
Lee, Rumi
Khanduri, Isha
Terranova, Christopher
Akdemir, Kadir
Chakravarti, Deepavali
Shang, Xiaoying
Spring, Denise J.
Wang, Y. Alan
DePinho, Ronald A.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10529424
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10529424
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-023-06254-7