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Mechanism of multidrug resistance to chemotherapy mediated by P‑glycoprotein (Review)

Mechanism of multidrug resistance to chemotherapy mediated by P‑glycoprotein (Review)

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10546381

Mechanism of multidrug resistance to chemotherapy mediated by P‑glycoprotein (Review)

About this item

Full title

Mechanism of multidrug resistance to chemotherapy mediated by P‑glycoprotein (Review)

Publisher

Athens: Spandidos Publications UK Ltd

Journal title

International journal of oncology, 2023-11, Vol.63 (5), Article 119

Language

English

Formats

Publication information

Publisher

Athens: Spandidos Publications UK Ltd

More information

Scope and Contents

Contents

Multidrug resistance (MDR) seriously limits the clinical application of chemotherapy. A mechanism underlying MDR is the overexpression of efflux transporters associated with chemotherapeutic drugs. P-glycoprotein (P-gp) is an ATP-binding cassette (ABC) transporter, which promotes MDR by pumping out chemotherapeutic drugs and reducing their intracel...

Alternative Titles

Full title

Mechanism of multidrug resistance to chemotherapy mediated by P‑glycoprotein (Review)

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10546381

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10546381

Other Identifiers

ISSN

1019-6439

E-ISSN

1791-2423

DOI

10.3892/ijo.2023.5567

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