Mechanism of multidrug resistance to chemotherapy mediated by P‑glycoprotein (Review)
Mechanism of multidrug resistance to chemotherapy mediated by P‑glycoprotein (Review)
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Publisher
Athens: Spandidos Publications UK Ltd
Journal title
Language
English
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Publisher
Athens: Spandidos Publications UK Ltd
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Scope and Contents
Contents
Multidrug resistance (MDR) seriously limits the clinical application of chemotherapy. A mechanism underlying MDR is the overexpression of efflux transporters associated with chemotherapeutic drugs. P-glycoprotein (P-gp) is an ATP-binding cassette (ABC) transporter, which promotes MDR by pumping out chemotherapeutic drugs and reducing their intracel...
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Full title
Mechanism of multidrug resistance to chemotherapy mediated by P‑glycoprotein (Review)
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10546381
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10546381
Other Identifiers
ISSN
1019-6439
E-ISSN
1791-2423
DOI
10.3892/ijo.2023.5567