Mechanism of multidrug resistance to chemotherapy mediated by P‑glycoprotein (Review)
Mechanism of multidrug resistance to chemotherapy mediated by P‑glycoprotein (Review)
About this item
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Author / Creator
Publisher
Athens: Spandidos Publications UK Ltd
Journal title
Language
English
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Publisher
Athens: Spandidos Publications UK Ltd
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Scope and Contents
Contents
Multidrug resistance (MDR) seriously limits the clinical application of chemotherapy. A mechanism underlying MDR is the overexpression of efflux transporters associated with chemotherapeutic drugs. P-glycoprotein (P-gp) is an ATP-binding cassette (ABC) transporter, which promotes MDR by pumping out chemotherapeutic drugs and reducing their intracel...
Alternative Titles
Full title
Mechanism of multidrug resistance to chemotherapy mediated by P‑glycoprotein (Review)
Authors, Artists and Contributors
Author / Creator
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10546381
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10546381
Other Identifiers
ISSN
1019-6439
E-ISSN
1791-2423
DOI
10.3892/ijo.2023.5567
