Seed amplification assay for the detection of pathologic alpha-synuclein aggregates in cerebrospinal...
Seed amplification assay for the detection of pathologic alpha-synuclein aggregates in cerebrospinal fluid
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Misfolded alpha-synuclein (αSyn) aggregates are a hallmark event in Parkinson’s disease (PD) and other synucleinopathies. Recently, αSyn seed amplification assays (αSyn-SAAs) have shown promise as a test for biochemical diagnosis of synucleinopathies. αSyn-SAAs use the intrinsic self-replicative nature of misfolded αSyn aggregates (seeds) to multip...
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Full title
Seed amplification assay for the detection of pathologic alpha-synuclein aggregates in cerebrospinal fluid
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10561622
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10561622
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ISSN
1754-2189
E-ISSN
1750-2799
DOI
10.1038/s41596-022-00787-3
