Ex vivo drug sensitivity screening predicts response to temozolomide in glioblastoma patients and id...
Ex vivo drug sensitivity screening predicts response to temozolomide in glioblastoma patients and identifies candidate biomarkers
About this item
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Author / Creator
GLIOTRAIN consortium , Ntafoulis, Ioannis , Kleijn, Anne , Ju, Jie , Jimenez-Cowell, Kevin , Fabro, Federica , Klein, Michelle , Chi Yen, Romain Tching , Balvers, Rutger K. , Li, Yunlei , Stubbs, Andrew P. , Kers, Trisha V. , Kros, Johan M. , Lawler, Sean E. , Beerepoot, Laurens V. , Kremer, Andreas , Idbaih, Ahmed , Verreault, Maite , Byrne, Annette T. , O’Farrell, Alice C. , Connor, Kate , Biswas, Archita , Salvucci, Manuela , Prehn, Jochen H. M. , Lambrechts, Diether , Dilcan, Gonca , Lodi, Francesca , Arijs, Ingrid , van den Bent, Martin J. , Dirven, Clemens M. F. , Leenstra, Sieger and Lamfers, Martine L. M.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Background
Patient-derived glioma stem-like cells (GSCs) have become the gold-standard in neuro-oncological research; however, it remains to be established whether loss of in situ microenvironment affects the clinically-predictive value of this model. We implemented a GSC monolayer system to investigate in situ
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in vitro molecular corresp...
Alternative Titles
Full title
Ex vivo drug sensitivity screening predicts response to temozolomide in glioblastoma patients and identifies candidate biomarkers
Authors, Artists and Contributors
Author / Creator
Ntafoulis, Ioannis
Kleijn, Anne
Ju, Jie
Jimenez-Cowell, Kevin
Fabro, Federica
Klein, Michelle
Chi Yen, Romain Tching
Balvers, Rutger K.
Li, Yunlei
Stubbs, Andrew P.
Kers, Trisha V.
Kros, Johan M.
Lawler, Sean E.
Beerepoot, Laurens V.
Kremer, Andreas
Idbaih, Ahmed
Verreault, Maite
Byrne, Annette T.
O’Farrell, Alice C.
Connor, Kate
Biswas, Archita
Salvucci, Manuela
Prehn, Jochen H. M.
Lambrechts, Diether
Dilcan, Gonca
Lodi, Francesca
Arijs, Ingrid
van den Bent, Martin J.
Dirven, Clemens M. F.
Leenstra, Sieger
Lamfers, Martine L. M.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10575865
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10575865
Other Identifiers
ISSN
0007-0920
E-ISSN
1532-1827
DOI
10.1038/s41416-023-02402-y
