Assessing QTc Effects of Vericiguat Using Two Different Concentration-QTc Modeling Approaches
Assessing QTc Effects of Vericiguat Using Two Different Concentration-QTc Modeling Approaches
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Publisher
Cham: Springer International Publishing
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Language
English
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Publisher
Cham: Springer International Publishing
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Contents
Background and Objectives
Vericiguat is a soluble guanylate cyclase stimulator indicated to reduce the risk of cardiovascular death and hospitalization due to heart failure. A dedicated QTc study in patients with chronic coronary syndromes demonstrated no clinically relevant QTc effect of vericiguat for exposures across the therapeutic dose rang...
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Assessing QTc Effects of Vericiguat Using Two Different Concentration-QTc Modeling Approaches
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10581916
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10581916
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ISSN
0312-5963
E-ISSN
1179-1926
DOI
10.1007/s40262-023-01282-y