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Assessing QTc Effects of Vericiguat Using Two Different Concentration-QTc Modeling Approaches

Assessing QTc Effects of Vericiguat Using Two Different Concentration-QTc Modeling Approaches

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10581916

Assessing QTc Effects of Vericiguat Using Two Different Concentration-QTc Modeling Approaches

About this item

Full title

Assessing QTc Effects of Vericiguat Using Two Different Concentration-QTc Modeling Approaches

Publisher

Cham: Springer International Publishing

Journal title

Clinical pharmacokinetics, 2023-11, Vol.62 (11), p.1639-1648

Language

English

Formats

Publication information

Publisher

Cham: Springer International Publishing

More information

Scope and Contents

Contents

Background and Objectives
Vericiguat is a soluble guanylate cyclase stimulator indicated to reduce the risk of cardiovascular death and hospitalization due to heart failure. A dedicated QTc study in patients with chronic coronary syndromes demonstrated no clinically relevant QTc effect of vericiguat for exposures across the therapeutic dose rang...

Alternative Titles

Full title

Assessing QTc Effects of Vericiguat Using Two Different Concentration-QTc Modeling Approaches

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10581916

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10581916

Other Identifiers

ISSN

0312-5963

E-ISSN

1179-1926

DOI

10.1007/s40262-023-01282-y

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