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Irinotecan-Induced Toxicity: A Pharmacogenetic Study Beyond UGT1A1

Irinotecan-Induced Toxicity: A Pharmacogenetic Study Beyond UGT1A1

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10582127

Irinotecan-Induced Toxicity: A Pharmacogenetic Study Beyond UGT1A1

About this item

Full title

Irinotecan-Induced Toxicity: A Pharmacogenetic Study Beyond UGT1A1

Publisher

Cham: Springer International Publishing

Journal title

Clinical pharmacokinetics, 2023-11, Vol.62 (11), p.1589-1597

Language

English

Formats

Publication information

Publisher

Cham: Springer International Publishing

More information

Scope and Contents

Contents

Background and objective
Side effects of irinotecan treatment can be dose limiting and may impair quality of life. In this study, we investigated the correlation between single nucleotide polymorphisms (SNPs) in genes encoding enzymes involved in the irinotecan metabolism and transport, outside
UGT1A1
, and irinotecan-related toxicity. We...

Alternative Titles

Full title

Irinotecan-Induced Toxicity: A Pharmacogenetic Study Beyond UGT1A1

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10582127

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10582127

Other Identifiers

ISSN

0312-5963

E-ISSN

1179-1926

DOI

10.1007/s40262-023-01279-7

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