Rare Heterozygous Loss-of-Function Variants in the Human GLP-1 Receptor Are Not Associated With Card...
Rare Heterozygous Loss-of-Function Variants in the Human GLP-1 Receptor Are Not Associated With Cardiometabolic Phenotypes
About this item
Full title
Author / Creator
Melchiorsen, Josefine U , Sørensen, Kimmie V , Bork-Jensen, Jette , Kizilkaya, Hüsün S , Gasbjerg, Lærke S , Hauser, Alexander S , Rungby, Jørgen , Sørensen, Henrik T , Vaag, Allan , Nielsen, Jens S , Pedersen, Oluf , Linneberg, Allan , Hartmann, Bolette , Gjesing, Anette P , Holst, Jens J , Hansen, Torben , Rosenkilde, Mette M and Grarup, Niels
Publisher
US: Oxford University Press
Journal title
Language
English
Formats
Publication information
Publisher
US: Oxford University Press
Subjects
More information
Scope and Contents
Contents
Abstract
Context
Lost glucagon-like peptide 1 receptor (GLP-1R) function affects human physiology.
Objective
This work aimed to identify coding nonsynonymous GLP1R variants in Danish individuals to link their in vitro phenotypes and clinical phenotypic associations.
Methods
We sequenced GLP1R in 8642 Danish individuals with type 2...
Alternative Titles
Full title
Rare Heterozygous Loss-of-Function Variants in the Human GLP-1 Receptor Are Not Associated With Cardiometabolic Phenotypes
Authors, Artists and Contributors
Author / Creator
Sørensen, Kimmie V
Bork-Jensen, Jette
Kizilkaya, Hüsün S
Gasbjerg, Lærke S
Hauser, Alexander S
Rungby, Jørgen
Sørensen, Henrik T
Vaag, Allan
Nielsen, Jens S
Pedersen, Oluf
Linneberg, Allan
Hartmann, Bolette
Gjesing, Anette P
Holst, Jens J
Hansen, Torben
Rosenkilde, Mette M
Grarup, Niels
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10584003
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10584003
Other Identifiers
ISSN
0021-972X
E-ISSN
1945-7197
DOI
10.1210/clinem/dgad290
