Prolonged hypoxia alleviates prolyl hydroxylation-mediated suppression of RIPK1 to promote necroptos...
Prolonged hypoxia alleviates prolyl hydroxylation-mediated suppression of RIPK1 to promote necroptosis and inflammation
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Author / Creator
Zhang, Tao , Xu, Daichao , Liu, Jianping , Wang, Min , Duan, Li-Juan , Liu, Min , Meng, Huyan , Zhuang, Yuan , Wang, Huibing , Wang, Yingnan , Lv, Mingming , Zhang, Zhengyi , Hu, Jia , Shi, Linyu , Guo, Rui , Xie, Xingxing , Liu, Hui , Erickson, Emily , Wang, Yaru , Yu, Wenyu , Dang, Fabin , Guan, Dongxian , Jiang, Cong , Dai, Xiaoming , Inuzuka, Hiroyuki , Yan, Peiqiang , Wang, Jingchao , Babuta, Mrigya , Lian, Gewei , Tu, Zhenbo , Miao, Ji , Szabo, Gyongyi , Fong, Guo-Hua , Karnoub, Antoine E. , Lee, Yu-Ru , Pan, Lifeng , Kaelin, William G. , Yuan, Junying and Wei, Wenyi
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
The prolyl hydroxylation of hypoxia-inducible factor 1α (HIF-1α) mediated by the EGLN–pVHL pathway represents a classic signalling mechanism that mediates cellular adaptation under hypoxia. Here we identify RIPK1, a known regulator of cell death mediated by tumour necrosis factor receptor 1 (TNFR1), as a target of EGLN1–pVHL. Prolyl hydroxylation o...
Alternative Titles
Full title
Prolonged hypoxia alleviates prolyl hydroxylation-mediated suppression of RIPK1 to promote necroptosis and inflammation
Authors, Artists and Contributors
Author / Creator
Xu, Daichao
Liu, Jianping
Wang, Min
Duan, Li-Juan
Liu, Min
Meng, Huyan
Zhuang, Yuan
Wang, Huibing
Wang, Yingnan
Lv, Mingming
Zhang, Zhengyi
Hu, Jia
Shi, Linyu
Guo, Rui
Xie, Xingxing
Liu, Hui
Erickson, Emily
Wang, Yaru
Yu, Wenyu
Dang, Fabin
Guan, Dongxian
Jiang, Cong
Dai, Xiaoming
Inuzuka, Hiroyuki
Yan, Peiqiang
Wang, Jingchao
Babuta, Mrigya
Lian, Gewei
Tu, Zhenbo
Miao, Ji
Szabo, Gyongyi
Fong, Guo-Hua
Karnoub, Antoine E.
Lee, Yu-Ru
Pan, Lifeng
Kaelin, William G.
Yuan, Junying
Wei, Wenyi
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10617019
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10617019
Other Identifiers
ISSN
1465-7392,1476-4679
E-ISSN
1476-4679
DOI
10.1038/s41556-023-01170-4
