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46 results for Inuzuka,+Hiroyuki

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ArticlesPeer ReviewedFull Text
Acetylation-dependent regulation of PD-L1 nuclear translocation dictates the efficacy of anti-PD-1 immunotherapy
Author / Creator:Gao, Yang ; Nihira, Naoe Taira ; Bu, Xia ; Chu, Chen ; Zhang, Jinfang ; Kolodziejczyk, Aleksandra ; Fan, Yizeng ; Chan, Ngai Ting ; Ma, Leina ; Liu, Jing ; Wang, Dong ; Dai, Xiaoming ; Liu, Huadong ; Ono, Masaya ; Nakanishi, Akira ; Inuzuka, Hiroyuki ; North, Brian J. ; Huang, Yu-Han ; Sharma, Samanta ; Geng, Yan ; Xu, Wei ; Liu, X. Shirley ; Li, Lei ; Miki, Yoshio ; Sicinski, Piotr ; Freeman, Gordon J. ; Wei, Wenyi
Publisher:London: Nature Publishing Group UK
Journal title:Nature cell biology, 2020-09, Vol.22 (9), p.1064-1075
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Delayed fluorescence from inverted singlet and triplet excited states
Author / Creator:Aizawa, Naoya ; Pu, Yong-Jin ; Harabuchi, Yu ; Nihonyanagi, Atsuko ; Ibuka, Ryotaro ; Inuzuka, Hiroyuki ; Dhara, Barun ; Koyama, Yuki ; Nakayama, Ken-ichi ; Maeda, Satoshi ; Araoka, Fumito ; Miyajima, Daigo
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2022-09, Vol.609 (7927), p.502-506
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Skp2 dictates cell cycle-dependent metabolic oscillation between glycolysis and TCA cycle
Author / Creator:Liu, Jing ; Peng, Yunhua ; Shi, Le ; Wan, Lixin ; Inuzuka, Hiroyuki ; Long, Jiangang ; Guo, Jianping ; Zhang, Jinfang ; Yuan, Min ; Zhang, Shuangxi ; Wang, Xun ; Gao, Jing ; Dai, Xiangpeng ; Furumoto, Shozo ; Jia, Lijun ; Pandolfi, Pier Paolo ; Asara, John M. ; Kaelin, William G. ; Liu, Jiankang ; Wei, Wenyi
Publisher:Singapore: Springer Singapore
Journal title:Cell research, 2021-01, Vol.31 (1), p.80-93
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Molecular Subtypes and Targeted Therapeutic Strategies in Small Cell Lung Cancer: Advances, Challenges, and Future Perspectives
Author / Creator:Huang, Daoyuan ; Wang, Jingchao ; Chen, Li ; Jiang, Weiwei ; Inuzuka, Hiroyuki ; Simon, David K. ; Wei, Wenyi
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2025-04, Vol.30 (8), p.1731
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Inhibition of CK1ε potentiates the therapeutic efficacy of CDK4/6 inhibitor in breast cancer
Author / Creator:Dang, Fabin ; Nie, Li ; Zhou, Jin ; Shimizu, Kouhei ; Chu, Chen ; Wu, Zhong ; Fassl, Anne ; Ke, Shizhong ; Wang, Yuangao ; Zhang, Jinfang ; Zhang, Tao ; Tu, Zhenbo ; Inuzuka, Hiroyuki ; Sicinski, Piotr ; Bass, Adam J. ; Wei, Wenyi
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-09, Vol.12 (1), p.5386-15, Article 5386
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pVHL suppresses kinase activity of Akt in a proline-hydroxylation-dependent manner
Author / Creator:Guo, Jianping ; Chakraborty, Abhishek A. ; Liu, Pengda ; Gan, Wenjian ; Zheng, Xingnan ; Inuzuka, Hiroyuki ; Wang, Bin ; Zhang, Jinfang ; Zhang, Linli ; Yuan, Min ; Novak, Jesse ; Cheng, Jin Q. ; Toker, Alex ; Signoretti, Sabina ; Zhang, Qing ; Asara, John M. ; Kaelin, William G. ; Wei, Wenyi
Publisher:United States: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2016-08, Vol.353 (6302), p.929-932
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SCFFBW7 regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction
Author / Creator:Inuzuka, Hiroyuki ; Shaik, Shavali ; Onoyama, Ichiro ; Gao, Daming ; Tseng, Alan ; Maser, Richard S. ; Zhai, Bo ; Wan, Lixin ; Gutierrez, Alejandro ; Lau, Alan W. ; Xiao, Yonghong ; Christie, Amanda L. ; Aster, Jon ; Settleman, Jeffrey ; Gygi, Steven P. ; Kung, Andrew L. ; Look, Thomas ; Nakayama, Keiichi I. ; DePinho, Ronald A. ; Wei, Wenyi
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2011-03, Vol.471 (7336), p.104-109
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Cell-cycle-regulated activation of Akt kinase by phosphorylation at its carboxyl terminus
Author / Creator:Liu, Pengda ; Begley, Michael ; Michowski, Wojciech ; Inuzuka, Hiroyuki ; Ginzberg, Miriam ; Gao, Daming ; Tsou, Peiling ; Gan, Wenjian ; Papa, Antonella ; Kim, Byeong Mo ; Wan, Lixin ; Singh, Amrik ; Zhai, Bo ; Yuan, Min ; Wang, Zhiwei ; Gygi, Steven P. ; Lee, Tae Ho ; Lu, Kun-Ping ; Toker, Alex ; Pandolfi, Pier Paolo ; Asara, John M. ; Kirschner, Marc W. ; Sicinski, Piotr ; Cantley, Lewis ; Wei, Wenyi
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2014-04, Vol.508 (7497), p.541-545
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SCFFBW7-mediated degradation of Brg1 suppresses gastric cancer metastasis
Author / Creator:Huang, Li-Yu ; Zhao, Junjie ; Chen, Hao ; Wan, Lixin ; Inuzuka, Hiroyuki ; Guo, Jianping ; Fu, Xuhong ; Zhai, Yangyang ; Lu, Zhaoning ; Wang, Xuefei ; Han, Ze-Guang ; Sun, Yihong ; Wei, Wenyi
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2018-09, Vol.9 (1), p.1-12, Article 3569
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Phosphorylation by Akt1 promotes cytoplasmic localization of Skp2 and impairs APCCdh1-mediated Skp2 destruction
Author / Creator:Gao, Daming ; Inuzuka, Hiroyuki ; Tseng, Alan ; Chin, Rebecca Y. ; Toker, Alex ; Wei, Wenyi
Publisher:London: Nature Publishing Group UK
Journal title:Nature cell biology, 2009-04, Vol.11 (4), p.397-408
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Prolonged hypoxia alleviates prolyl hydroxylation-mediated suppression of RIPK1 to promote necroptosis and inflammation
Author / Creator:Zhang, Tao ; Xu, Daichao ; Liu, Jianping ; Wang, Min ; Duan, Li-Juan ; Liu, Min ; Meng, Huyan ; Zhuang, Yuan ; Wang, Huibing ; Wang, Yingnan ; Lv, Mingming ; Zhang, Zhengyi ; Hu, Jia ; Shi, Linyu ; Guo, Rui ; Xie, Xingxing ; Liu, Hui ; Erickson, Emily ; Wang, Yaru ; Yu, Wenyu ; Dang, Fabin ; Guan, Dongxian ; Jiang, Cong ; Dai, Xiaoming ; Inuzuka, Hiroyuki ; Yan, Peiqiang ; Wang, Jingchao ; Babuta, Mrigya ; Lian, Gewei ; Tu, Zhenbo ; Miao, Ji ; Szabo, Gyongyi ; Fong, Guo-Hua ; Karnoub, Antoine E. ; Lee, Yu-Ru ; Pan, Lifeng ; Kaelin, William G. ; Yuan, Junying ; Wei, Wenyi
Publisher:London: Nature Publishing Group UK
Journal title:Nature cell biology, 2023-07, Vol.25 (7), p.950-962
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G1 cyclins link proliferation, pluripotency and differentiation of embryonic stem cells
Author / Creator:Liu, Lijun ; Michowski, Wojciech ; Inuzuka, Hiroyuki ; Shimizu, Kouhei ; Nihira, Naoe Taira ; Chick, Joel M. ; Li, Na ; Geng, Yan ; Meng, Alice Y. ; Ordureau, Alban ; Kołodziejczyk, Aleksandra ; Ligon, Keith L. ; Bronson, Roderick T. ; Polyak, Kornelia ; Harper, J. Wade ; Gygi, Steven P. ; Wei, Wenyi ; Sicinski, Piotr
Publisher:London: Nature Publishing Group UK
Journal title:Nature cell biology, 2017-03, Vol.19 (3), p.177-188
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Author Correction: Skp2 dictates cell cycle-dependent metabolic oscillation between glycolysis and TCA cycle
Author / Creator:Liu, Jing ; Peng, Yunhua ; Shi, Le ; Wan, Lixin ; Inuzuka, Hiroyuki ; Long, Jiangang ; Guo, Jianping ; Zhang, Jinfang ; Yuan, Min ; Zhang, Shuangxi ; Wang, Xun ; Gao, Jing ; Dai, Xiangpeng ; Furumoto, Shozo ; Jia, Lijun ; Pandolfi, Pier Paolo ; Asara, John M. ; Kaelin, William G. ; Liu, Jiankang ; Wei, Wenyi
Publisher:Singapore: Springer Singapore
Journal title:Cell research, 2021-01, Vol.31 (1), p.104-104
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SCFβ‐TrCP ubiquitinates CHK1 in an AMPK‐dependent manner in response to glucose deprivation
Author / Creator:Ma, Ying ; Cui, Danrui ; Xiong, Xiufang ; Inuzuka, Hiroyuki ; Wei, Wenyi ; Sun, Yi ; North, Brian J. ; Zhao, Yongchao
Publisher:United States: John Wiley & Sons, Inc
Journal title:Molecular oncology, 2019-02, Vol.13 (2), p.307-321
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Targeting the PARylation-Dependent Ubiquitination Signaling Pathway for Cancer Therapies
Author / Creator:Huang, Daoyuan ; Wang, Jingchao ; Chen, Li ; Jiang, Weiwei ; Inuzuka, Hiroyuki ; Simon, David K ; Wei, Wenyi
Publisher:Switzerland: MDPI AG
Journal title:Biomolecules (Basel, Switzerland), 2025-02, Vol.15 (2), p.237
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Skp2 dictates cell cycle-dependent metabolic oscillation between glycolysis and TCA cycle
Author / Creator:Liu, Jing ; Peng, Yunhua ; Shi, Le ; Wan, Lixin ; Inuzuka, Hiroyuki ; Long, Jiangang ; Guo, Jianping ; Zhang, Jinfang ; Yuan, Min ; Zhang, Shuangxi ; Wang, Xun ; Gao, Jing ; Dai, Xiangpeng ; Furumoto, Shozo ; Jia, Lijun ; Pandolfi, Pier Paolo ; Asara, John M. ; Kaelin, William G. ; Liu, Jiankang ; Wei, Wenyi
Journal title:Cell research, 2021-01, Vol.31 (1), p.80-93
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Author Correction: Sin1 phosphorylation impairs mTORC2 complex integrity and inhibits downstream Akt signalling to suppress tumorigenesis
Author / Creator:Liu, Pengda ; Gan, Wenjian ; Inuzuka, Hiroyuki ; Lazorchak, Adam S. ; Gao, Daming ; Arojo, Omotooke ; Liu, Dou ; Wan, Lixin ; Zhai, Bo ; Yu, Yonghao ; Yuan, Min ; Kim, Byeong Mo ; Shaik, Shavali ; Menon, Suchithra ; Gygi, Steven P. ; Lee, Tae Ho ; Asara, John M. ; Manning, Brendan D. ; Blenis, John ; Su, Bing ; Wei, Wenyi
Publisher:London: Nature Publishing Group UK
Journal title:Nature cell biology, 2019-05, Vol.21 (5), p.662-663
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Regulation of APC^cdh1 E3 ligase activity by the Fbw7/cyclin E signaling axis contributes to the tumor suppressor function of Fbw7
Author / Creator:Alan WLau Hiroyuki Inuzuka Hidefumi Fukushima LixinWan Pengda Liu Daming Gao Yi Sun Wenyi Wei
Journal title:细胞研究：英文版, 2013-07 (7), p.947-961
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SCF β-TRCP E3 ubiquitin ligase targets the tumor suppressor ZNRF3 for ubiquitination and degradation
Author / Creator:Ci, Yanpeng ; Li, Xiaoning ; Chen, Maorong ; Zhong, Jiateng ; North, Brian J. ; Inuzuka, Hiroyuki ; He, Xi ; Li, Yu ; Guo, Jianping ; Dai, Xiangpeng
Publisher:Beijing: Higher Education Press
Journal title:Protein & cell, 2018-10, Vol.9 (10), p.879-889
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Akt finds its new path to regulate cell cycle through modulating Skp2 activity and its destruction by APC/Cdh1
Author / Creator:Gao, Daming ; Inuzuka, Hiroyuki ; Tseng, Alan ; Wei, Wenyi
Publisher:England: BioMed Central Ltd
Journal title:Cell division, 2009-06, Vol.4 (1), p.11-11, Article 11
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Showing 1 to 20 of 46 results

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Acetylation-dependent regulation of PD-L1 nuclear translocation dictates the efficacy of anti-PD-1 immunotherapy

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Delayed fluorescence from inverted singlet and triplet excited states

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Skp2 dictates cell cycle-dependent metabolic oscillation between glycolysis and TCA cycle

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Molecular Subtypes and Targeted Therapeutic Strategies in Small Cell Lung Cancer: Advances, Challenges, and Future Perspectives

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Inhibition of CK1ε potentiates the therapeutic efficacy of CDK4/6 inhibitor in breast cancer

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pVHL suppresses kinase activity of Akt in a proline-hydroxylation-dependent manner

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SCFFBW7 regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction

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Cell-cycle-regulated activation of Akt kinase by phosphorylation at its carboxyl terminus

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SCFFBW7-mediated degradation of Brg1 suppresses gastric cancer metastasis

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Phosphorylation by Akt1 promotes cytoplasmic localization of Skp2 and impairs APCCdh1-mediated Skp2 destruction

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Prolonged hypoxia alleviates prolyl hydroxylation-mediated suppression of RIPK1 to promote necroptosis and inflammation

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G1 cyclins link proliferation, pluripotency and differentiation of embryonic stem cells

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Author Correction: Skp2 dictates cell cycle-dependent metabolic oscillation between glycolysis and TCA cycle

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SCFβ‐TrCP ubiquitinates CHK1 in an AMPK‐dependent manner in response to glucose deprivation

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Targeting the PARylation-Dependent Ubiquitination Signaling Pathway for Cancer Therapies

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Skp2 dictates cell cycle-dependent metabolic oscillation between glycolysis and TCA cycle

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Author Correction: Sin1 phosphorylation impairs mTORC2 complex integrity and inhibits downstream Akt signalling to suppress tumorigenesis

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Regulation of APC^cdh1 E3 ligase activity by the Fbw7/cyclin E signaling axis contributes to the tumor suppressor function of Fbw7

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SCF β-TRCP E3 ubiquitin ligase targets the tumor suppressor ZNRF3 for ubiquitination and degradation

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Akt finds its new path to regulate cell cycle through modulating Skp2 activity and its destruction by APC/Cdh1

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