Leptin receptor+ cells promote bone marrow innervation and regeneration by synthesizing nerve growth...
Leptin receptor+ cells promote bone marrow innervation and regeneration by synthesizing nerve growth factor
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
The bone marrow contains peripheral nerves that promote haematopoietic regeneration after irradiation or chemotherapy (myeloablation), but little is known about how this is regulated. Here we found that nerve growth factor (NGF) produced by leptin receptor-expressing (LepR
+
) stromal cells is required to maintain nerve fibres in adult bone m...
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Full title
Leptin receptor+ cells promote bone marrow innervation and regeneration by synthesizing nerve growth factor
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10709146
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10709146
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ISSN
1465-7392
E-ISSN
1476-4679
DOI
10.1038/s41556-023-01284-9