cAMP-mediated upregulation of HCN channels in VTA dopamine neurons promotes cocaine reinforcement
cAMP-mediated upregulation of HCN channels in VTA dopamine neurons promotes cocaine reinforcement
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Chronic cocaine exposure induces enduring neuroadaptations that facilitate motivated drug taking. Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels are known to modulate neuronal firing and pacemaker activity in ventral tegmental area (VTA) dopamine neurons. However, it remained unknown whether cocaine self-administration affects H...
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cAMP-mediated upregulation of HCN channels in VTA dopamine neurons promotes cocaine reinforcement
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10730389
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10730389
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ISSN
1359-4184
E-ISSN
1476-5578
DOI
10.1038/s41380-023-02290-x