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Repeated Omicron exposures override ancestral SARS-CoV-2 immune imprinting

Repeated Omicron exposures override ancestral SARS-CoV-2 immune imprinting

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10764275

Repeated Omicron exposures override ancestral SARS-CoV-2 immune imprinting

About this item

Full title

Repeated Omicron exposures override ancestral SARS-CoV-2 immune imprinting

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2024-01, Vol.625 (7993), p.148-156

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The continuing emergence of SARS-CoV-2 variants highlights the need to update COVID-19 vaccine compositions. However, immune imprinting induced by vaccination based on the ancestral (hereafter referred to as WT) strain would compromise the antibody response to Omicron-based boosters
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. Vaccination strategies to counter immune impri...

Alternative Titles

Full title

Repeated Omicron exposures override ancestral SARS-CoV-2 immune imprinting

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10764275

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10764275

Other Identifiers

ISSN

0028-0836,1476-4687

E-ISSN

1476-4687

DOI

10.1038/s41586-023-06753-7

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