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Integrating TSPO PET imaging and transcriptomics to unveil the role of neuroinflammation and amyloid...

Integrating TSPO PET imaging and transcriptomics to unveil the role of neuroinflammation and amyloid...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10774172

Integrating TSPO PET imaging and transcriptomics to unveil the role of neuroinflammation and amyloid-β deposition in Alzheimer’s disease

About this item

Full title

Integrating TSPO PET imaging and transcriptomics to unveil the role of neuroinflammation and amyloid-β deposition in Alzheimer’s disease

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

Journal title

European journal of nuclear medicine and molecular imaging, 2024-01, Vol.51 (2), p.455-467

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

More information

Scope and Contents

Contents

Purpose
Despite the revealed role of immunological dysfunctions in the development and progression of Alzheimer’s disease (AD) through animal and postmortem investigations, direct evidence regarding the impact of genetic factors on microglia response and amyloid-β (Aβ) deposition in AD individuals is lacking. This study aims to elucidate this me...

Alternative Titles

Full title

Integrating TSPO PET imaging and transcriptomics to unveil the role of neuroinflammation and amyloid-β deposition in Alzheimer’s disease

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10774172

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10774172

Other Identifiers

ISSN

1619-7070

E-ISSN

1619-7089

DOI

10.1007/s00259-023-06446-3

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