Scrutiny of genome‐wide somatic mutation profiles in centenarians identifies the key genomic regions...
Scrutiny of genome‐wide somatic mutation profiles in centenarians identifies the key genomic regions for human longevity
About this item
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Publisher
England: John Wiley & Sons, Inc
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Language
English
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Publisher
England: John Wiley & Sons, Inc
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Scope and Contents
Contents
Somatic mutations accumulate with age and are associated closely with human health, their characterization in longevity cohorts remains largely unknown. Here, by analyzing whole genome somatic mutation profiles in 73 centenarians and 51 younger controls in China, we found that centenarian genomes are characterized by a markedly skewed distribution...
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Full title
Scrutiny of genome‐wide somatic mutation profiles in centenarians identifies the key genomic regions for human longevity
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10776117
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10776117
Other Identifiers
ISSN
1474-9718,1474-9726
E-ISSN
1474-9726
DOI
10.1111/acel.13916
